Pegivirus avoids immune recognition but does not attenuate acute-phase disease in a macaque model of HIV infection

Human pegivirus (HPgV) protects HIV+ people from HIV-associated disease, but the mechanism of this protective effect remains poorly understood. We sequentially infected cynomolgus macaques with simian pegivirus (SPgV) and simian immunodeficiency virus (SIV) to model HIV+HPgV co-infection. SPgV had n...

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Udgivet i:PLoS Pathog
Main Authors: Bailey, Adam L., Buechler, Connor R., Matson, Daniel R., Peterson, Eric J., Brunner, Kevin G., Mohns, Mariel S., Breitbach, Meghan, Stewart, Laurel M., Ericsen, Adam J., Newman, Christina M., Koenig, Michelle R., Mohr, Emma, Tan, John, Capuano, Saverio, Simmons, Heather A., Yang, David T., O’Connor, David H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675458/
https://ncbi.nlm.nih.gov/pubmed/29073258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006692
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