Growth arrest and DNA damage-inducible 45α protects against nonalcoholic steatohepatitis induced by methionine- and choline-deficient diet

Growth arrest and DNA damage-inducible 45 α (Gadd45α) is a stress-inducible protein that plays an important role in cell survival/death and DNA repair, but its contribution to the development of nonalcoholic steatohepatitis (NASH) has not been investigated. C57BL/6 Gadd45a-null and wild-type (WT) mi...

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Veröffentlicht in:Biochim Biophys Acta
Hauptverfasser: Tanaka, Naoki, Takahashi, Shogo, Hu, Xiao, Yu, Lu, Fujimori, Naoyuki, Golla, Srujana, Fang, Zhong-Ze, Aoyama, Toshifumi, Krausz, Kristopher W., Gonzalez, Frank J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675002/
https://ncbi.nlm.nih.gov/pubmed/28844958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.08.017
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