Specific Contribution of Methionine and Choline in Nutritional Nonalcoholic Steatohepatitis: IMPACT ON MITOCHONDRIAL S-ADENOSYL-l-METHIONINE AND GLUTATHIONE

The pathogenesis and treatment of nonalcoholic steatohepatitis (NASH) are not well established. Feeding a diet deficient in both methionine and choline (MCD) is one of the most common models of NASH, which is characterized by steatosis, mitochondrial dysfunction, hepatocellular injury, oxidative str...

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Main Authors: Caballero, Francisco, Fernández, Anna, Matías, Nuria, Martínez, Laura, Fucho, Raquel, Elena, Montserrat, Caballeria, Joan, Morales, Albert, Fernández-Checa, José C., García-Ruiz, Carmen
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Lipids
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881778/
https://ncbi.nlm.nih.gov/pubmed/20395294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.099333
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