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Low-dose post-transplant cyclophosphamide can mitigate GVHD and enhance the G-CSF/ATG induced GVHD protective activity and improve haploidentical transplant outcomes

Use of high-dose, post-transplant cyclophosphamide (PTCy) results in low rates of graft-versus-host-disease (GVHD) and favorable immune reconstitution, although with higher rates of relapse and somewhat high rates of graft failure. We hypothesized that permissible dose reduction of PTCy might be fea...

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Publicat a:Oncoimmunology
Autors principals: Wang, Yu, Chang, Ying-Jun, Chen, Lu, Xu, Lan-Ping, Bian, Zhi-Lei, Zhang, Xiao-Hui, Yan, Chen-Hua, Liu, Kai-Yan, Huang, Xiao-Jun
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674947/
https://ncbi.nlm.nih.gov/pubmed/29147612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1356152
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