Postsynaptic adhesion GPCR latrophilin-2 mediates target recognition in entorhinal-hippocampal synapse assembly

Synapse assembly likely requires postsynaptic target recognition by incoming presynaptic afferents. Using newly generated conditional knock-in and knockout mice, we show in this study that latrophilin-2 (Lphn2), a cell-adhesion G protein–coupled receptor and presumptive α-latrotoxin receptor, contro...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Anderson, Garret R., Maxeiner, Stephan, Sando, Richard, Tsetsenis, Theodoros, Malenka, Robert C., Südhof, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674891/
https://ncbi.nlm.nih.gov/pubmed/28972101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201703042
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