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Crossed wires: 3D genome misfolding in human disease
Mammalian genomes are folded into unique topological structures that undergo precise spatiotemporal restructuring during healthy development. Here, we highlight recent advances in our understanding of how the genome folds inside the 3D nucleus and how these folding patterns are miswired during the o...
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| Publicado no: | J Cell Biol |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5674879/ https://ncbi.nlm.nih.gov/pubmed/28855250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201611001 |
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