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Cell–cell adhesion accounts for the different orientation of columnar and hepatocytic cell divisions

Mitotic spindle alignment with the basal or substrate-contacting domain ensures that dividing epithelial cells remain in the plane of the monolayer. Spindle orientation with respect to the substratum is established in metaphase coincident with maximal cell rounding, which enables unobstructed spindl...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Lázaro-Diéguez, Francisco, Müsch, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674875/
https://ncbi.nlm.nih.gov/pubmed/28887437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201608065
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