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Cell division orientation is coupled to cell–cell adhesion by the E-cadherin/LGN complex

Both cell–cell adhesion and oriented cell division play prominent roles in establishing tissue architecture, but it is unclear how they might be coordinated. Here, we demonstrate that the cell–cell adhesion protein E-cadherin functions as an instructive cue for cell division orientation. This is med...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Gloerich, Martijn, Bianchini, Julie M., Siemers, Kathleen A., Cohen, Daniel J., Nelson, W. James
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216124/
https://ncbi.nlm.nih.gov/pubmed/28045117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13996
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