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Cell division orientation is coupled to cell–cell adhesion by the E-cadherin/LGN complex

Both cell–cell adhesion and oriented cell division play prominent roles in establishing tissue architecture, but it is unclear how they might be coordinated. Here, we demonstrate that the cell–cell adhesion protein E-cadherin functions as an instructive cue for cell division orientation. This is med...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Gloerich, Martijn, Bianchini, Julie M., Siemers, Kathleen A., Cohen, Daniel J., Nelson, W. James
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216124/
https://ncbi.nlm.nih.gov/pubmed/28045117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13996
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