Targeting of Immune Cells by Dual TLR2/7 Ligands Suppresses Features of Allergic Th2 Immune Responses in Mice

BACKGROUND: TLR ligands can promote Th1-biased immune responses, mimicking potent stimuli of viruses and bacteria. AIM: To investigate the adjuvant properties of dual TLR2/7 ligands compared to those of the mixture of both single ligands. METHODS: Dual TLR2/7 ligands: CL401, CL413, and CL531, includ...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Laiño, Jonathan, Wangorsch, Andrea, Blanco, Frank, Wolfheimer, Sonja, Krause, Maren, Flaczyk, Adam, Möller, Tobias-Maximilian, Tsai, Mindy, Galli, Stephen, Vieths, Stefan, Toda, Masako, Scheurer, Stephan, Schülke, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674512/
https://ncbi.nlm.nih.gov/pubmed/29204451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7983217
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