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A novel function of hepatocyte growth factor in the activation of checkpoint kinase 1 phosphorylation in colon cancer cells

The ATR/checkpoint kinase 1 (Chk1) pathway plays an essential role in modulating the DNA damage response and homologous recombination. Particularly, Chk1 phosphorylation is related to cancer prognosis and therapeutic resistance. Some receptor tyrosine kinases participate in the regulation of Chk1 ph...

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Bibliografske podrobnosti
izdano v:Mol Cell Biochem
Main Authors: Song, Na, Che, Xiaofang, Xu, Lu, Qu, Jinglei, Zheng, Huachuan, Hou, Kezuo, Qu, Xiujuan, Liu, Yunpeng
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674134/
https://ncbi.nlm.nih.gov/pubmed/28573382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-017-3075-0
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