A novel function of hepatocyte growth factor in the activation of checkpoint kinase 1 phosphorylation in colon cancer cells

The ATR/checkpoint kinase 1 (Chk1) pathway plays an essential role in modulating the DNA damage response and homologous recombination. Particularly, Chk1 phosphorylation is related to cancer prognosis and therapeutic resistance. Some receptor tyrosine kinases participate in the regulation of Chk1 ph...

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Publicado no:Mol Cell Biochem
Main Authors: Song, Na, Che, Xiaofang, Xu, Lu, Qu, Jinglei, Zheng, Huachuan, Hou, Kezuo, Qu, Xiujuan, Liu, Yunpeng
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674134/
https://ncbi.nlm.nih.gov/pubmed/28573382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-017-3075-0
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