Smoking induces DNA methylation changes in Multiple Sclerosis patients with exposure-response relationship

Cigarette smoking is an established environmental risk factor for Multiple Sclerosis (MS), a chronic inflammatory and neurodegenerative disease, although a mechanistic basis remains largely unknown. We aimed at investigating how smoking affects blood DNA methylation in MS patients, by assaying genom...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Marabita, Francesco, Almgren, Malin, Sjöholm, Louise K., Kular, Lara, Liu, Yun, James, Tojo, Kiss, Nimrod B., Feinberg, Andrew P., Olsson, Tomas, Kockum, Ingrid, Alfredsson, Lars, Ekström, Tomas J., Jagodic, Maja
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674007/
https://ncbi.nlm.nih.gov/pubmed/29109506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14788-w
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