Llwytho...
Knockdown of amyloid precursor protein increases calcium levels in the endoplasmic reticulum
Familial Alzheimer’s disease (AD) is caused by mutations in the genes that encode amyloid precursor protein (APP) and presenilins. Disturbances in calcium homeostasis have been observed in various cellular and animal models of AD and are proposed to underlie the pathogenesis of the disease. Furtherm...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Sci Rep |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Nature Publishing Group UK
2017
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5673940/ https://ncbi.nlm.nih.gov/pubmed/29109429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15166-2 |
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