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Competition between crystal and fibril formation in molecular mutations of amyloidogenic peptides

Amyloidogenic model peptides are invaluable for investigating assembly mechanisms in disease related amyloids and in protein folding. During aggregation, such peptides can undergo bifurcation leading to fibrils or crystals, however the mechanisms of fibril-to-crystal conversion are unclear. We navig...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Reynolds, Nicholas P., Adamcik, Jozef, Berryman, Joshua T., Handschin, Stephan, Zanjani, Ali Asghar Hakami, Li, Wen, Liu, Kun, Zhang, Afang, Mezzenga, Raffaele
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673901/
https://ncbi.nlm.nih.gov/pubmed/29109399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01424-4
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