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Acetylcholinesterase inhibition reveals endogenous nicotinic modulation of glutamate inputs to CA1 stratum radiatum interneurons in hippocampal slices

The involvement of brain nicotinic acetylcholine receptors (nAChRs) in the neurotoxicological effects of soman, a potent acetylcholinesterase (AChE) inhibitor and a chemical warfare agent, is not clear. This is partly due to a poor understanding of the role of AChE in brain nAChR-mediated functions....

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Detalhes bibliográficos
Publicado no:Neurotoxicology
Main Authors: Alkondon, Manickavasagom, Albuquerque, Edson X., Pereira, Edna F.R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673493/
https://ncbi.nlm.nih.gov/pubmed/23511125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2013.02.005
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