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Rnr1, but not Rnr3, facilitates the sustained telomerase-dependent elongation of telomeres
Ribonucleotide reductase (RNR) provides the precursors for the generation of dNTPs, which are required for DNA synthesis and repair. Here, we investigated the function of the major RNR subunits Rnr1 and Rnr3 in telomere elongation in budding yeast. We show that Rnr1 is essential for the sustained el...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5673236/ https://ncbi.nlm.nih.gov/pubmed/29069086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007082 |
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