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Local application of an ibandronate/collagen sponge improves femoral fracture healing in ovariectomized rats

Non-union is a major clinical problem in the healing of fractures, especially in patients with osteoporosis. The systemic administration of drugs is time consuming and large doses are demanding and act slowly, whereas local release acts rapidly, increases the quality and quantity of the bone tissue....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Guo, Jialiang, Zhang, Qi, Li, Jia, Liu, Yansong, Hou, Zhiyong, Chen, Wei, Jin, Lin, Tian, Ye, Ju, Linlin, Liu, Bo, Dong, Tianhua, Zhang, Fei, Zhang, Yingze
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673204/
https://ncbi.nlm.nih.gov/pubmed/29108027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187683
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