Local application of an ibandronate/collagen sponge improves femoral fracture healing in ovariectomized rats

Non-union is a major clinical problem in the healing of fractures, especially in patients with osteoporosis. The systemic administration of drugs is time consuming and large doses are demanding and act slowly, whereas local release acts rapidly, increases the quality and quantity of the bone tissue....

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Guo, Jialiang, Zhang, Qi, Li, Jia, Liu, Yansong, Hou, Zhiyong, Chen, Wei, Jin, Lin, Tian, Ye, Ju, Linlin, Liu, Bo, Dong, Tianhua, Zhang, Fei, Zhang, Yingze
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673204/
https://ncbi.nlm.nih.gov/pubmed/29108027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187683
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