Cooperation of IRAK1/4 inhibitor and ABT-737 in nanoparticles for synergistic therapy of T cell acute lymphoblastic leukemia

T cell acute lymphoblastic leukemia (T-ALL) is caused by clonal expansion of variant T cell progenitors and is considered as a high risk leukemia. Contemporary single chemotherapy has a limited effect due to dynamic and versatile properties of T-ALL. Here IRAK1/4 inhibitor and ABT-737 were co-encaps...

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Bibliographic Details
Published in:Int J Nanomedicine
Main Authors: Wu, Xiaoyan, Wang, Lin, Qiu, Yining, Zhang, Bingyu, Hu, Zhenhua, Jin, Runming
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2017
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673049/
https://ncbi.nlm.nih.gov/pubmed/29184402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S146875
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