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Determination of protonation states of iminosugar–enzyme complexes using photoinduced electron transfer
A series of N-alkylated analogues of 1-deoxynojirimycin containing a fluorescent 10-chloro-9-anthracene group in the N-alkyl substituent were prepared. The anthracene group acted as a reporting group for protonation at the nitrogen in the iminosugar because an unprotonated amine was found to quench...
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Publicado no: | Chem Sci |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Royal Society of Chemistry
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5672842/ https://ncbi.nlm.nih.gov/pubmed/29163889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01540b |
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