Constitutive Activation of Integrin α9 Augments Self-Directed Hyperplastic and Proinflammatory Properties of Fibroblast-like Synoviocytes of Rheumatoid Arthritis

Despite advances in the treatment of rheumatoid arthritis (RA), currently approved medications can have significant side effects due to their direct immunosuppressive activities. Additionally, current therapies do not address residual synovial inflammation. In this study, we evaluated the role of in...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Emori, Takashi, Hirose, Jun, Ise, Kotoko, Yomoda, Jun-ichiro, Kasahara, Michiko, Shinkuma, Tadanobu, Yoshitomi, Hiroyuki, Ito, Hiromu, Hashimoto, Motomu, Sugahara, Shingo, Fujita, Hirotada, Yamamoto, Nobuchika, Morita, Yoshiaki, Narumiya, Shuh, Aramori, Ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2017
Assuntos:
Autoimmunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672818/
https://ncbi.nlm.nih.gov/pubmed/29038247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700941
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