The novel resveratrol derivative 3,5-diethoxy-3′,4′-dihydroxy-trans-stilbene induces mitochondrial ROS-mediated ER stress and cell death in human hepatoma cells in vitro

Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a well-known polyphenol that is present in grapes, peanuts, pine seeds, and several other plants. Resveratrol exerts deleterious effects on various types of human cancer cells. Here, we analyzed the cell death-inducing mechanisms of resveratrol-006 (...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Park, Jae-woo, Choi, Woo-gyun, Lee, Phil-jun, Chung, Su-wol, Kim, Byung-sam, Chung, Hun-taeg, Cho, Sungchan, Kim, Jong-heon, Kang, Byoung-heon, Kim, Hyoungsu, Kim, Hong-pyo, Back, Sung-hoon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672065/
https://ncbi.nlm.nih.gov/pubmed/28795692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.106
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