The novel resveratrol derivative 3,5-diethoxy-3′,4′-dihydroxy-trans-stilbene induces mitochondrial ROS-mediated ER stress and cell death in human hepatoma cells in vitro

Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a well-known polyphenol that is present in grapes, peanuts, pine seeds, and several other plants. Resveratrol exerts deleterious effects on various types of human cancer cells. Here, we analyzed the cell death-inducing mechanisms of resveratrol-006 (...

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Publicat a:Acta Pharmacol Sin
Autors principals: Park, Jae-woo, Choi, Woo-gyun, Lee, Phil-jun, Chung, Su-wol, Kim, Byung-sam, Chung, Hun-taeg, Cho, Sungchan, Kim, Jong-heon, Kang, Byoung-heon, Kim, Hyoungsu, Kim, Hong-pyo, Back, Sung-hoon
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672065/
https://ncbi.nlm.nih.gov/pubmed/28795692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.106
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