Epidermal growth factor receptor inhibition downregulates Helicobacter pylori-induced epithelial inflammatory responses, DNA damage, and gastric carcinogenesis

OBJECTIVE: Gastric cancer is the third leading cause of cancer death worldwide and infection by Helicobacter pylori is the strongest risk factor. We have reported increased epidermal growth factor receptor (EGFR) phosphorylation in the H. pylori-induced human carcinogenesis cascade, and association...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Sierra, Johanna C., Asim, Mohammad, Verriere, Thomas G., Piazuelo, M. Blanca, Suarez, Giovanni, Romero-Gallo, Judith, Delgado, Alberto G., Wroblewski, Lydia E., Barry, Daniel P., Peek, Richard M., Gobert, Alain P., Wilson, Keith T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671361/
https://ncbi.nlm.nih.gov/pubmed/28473630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-312888
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