GYY4137, an H(2)S Slow-Releasing Donor, Prevents Nitrative Stress and α-Synuclein Nitration in an MPTP Mouse Model of Parkinson’s Disease

The neuromodulator hydrogen sulfide (H(2)S) was shown to exert neuroprotection in different models of Parkinson’s disease (PD) via its anti-inflammatory and anti-apoptotic properties. In this study, we evaluated the effect of an H(2)S slow-releasing compound GYY4137 (GYY) on a mouse PD model induced...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Hou, Xiaoou, Yuan, Yuqing, Sheng, Yulan, Yuan, Baoshi, Wang, Yali, Zheng, Jiyue, Liu, Chun-Feng, Zhang, Xiaohu, Hu, Li-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671206/
https://ncbi.nlm.nih.gov/pubmed/29163149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00741
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