Human CD141(+) Dendritic Cell and CD1c(+) Dendritic Cell Undergo Concordant Early Genetic Programming after Activation in Humanized Mice In Vivo

Human immune cell subsets develop in immunodeficient mice following reconstitution with human CD34(+) hematopoietic stem cells. These “humanized” mice are useful models to study human immunology and human-tropic infections, autoimmunity, and cancer. However, some human immune cell subsets are unable...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Minoda, Yoshihito, Virshup, Isaac, Leal Rojas, Ingrid, Haigh, Oscar, Wong, Yide, Miles, John J., Wells, Christine A., Radford, Kristen J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5670352/
https://ncbi.nlm.nih.gov/pubmed/29163495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01419
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