Butyrate Conditions Human Dendritic Cells to Prime Type 1 Regulatory T Cells via both Histone Deacetylase Inhibition and G Protein-Coupled Receptor 109A Signaling

Recently, it has become clear that short-chain fatty acids (SCFAs), and in particular butyrate, have anti-inflammatory properties. Murine studies have shown that butyrate can promote regulatory T cells via the induction of tolerogenic dendritic cells (DCs). However, the effects of SCFAs on human DCs...

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發表在:Front Immunol
Main Authors: Kaisar, Maria M. M., Pelgrom, Leonard R., van der Ham, Alwin J., Yazdanbakhsh, Maria, Everts, Bart
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2017
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5670331/
https://ncbi.nlm.nih.gov/pubmed/29163504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01429
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