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Structural basis for mutually exclusive co-transcriptional nuclear cap-binding complexes with either NELF-E or ARS2

Pol II transcribes diverse classes of RNAs that need to be directed into the appropriate nuclear maturation pathway. All nascent Pol II transcripts are 5′-capped and the cap is immediately sequestered by the nuclear cap-binding complex (CBC). Mutually exclusive interactions of CBC with different par...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Schulze, Wiebke Manuela, Cusack, Stephen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5670239/
https://ncbi.nlm.nih.gov/pubmed/29101316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01402-w
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