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Folding of a bacterial integral outer membrane protein is initiated in the periplasm

The Bam complex promotes the insertion of β-barrel proteins into the bacterial outer membrane, but it is unclear whether it threads β-strands into the lipid bilayer in a stepwise fashion or catalyzes the insertion of pre-folded substrates. Here, to distinguish between these two possibilities, we ana...

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Publicat a:Nat Commun
Autors principals: Sikdar, Rakesh, Peterson, Janine H., Anderson, D. Eric, Bernstein, Harris D.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5670179/
https://ncbi.nlm.nih.gov/pubmed/29101319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01246-4
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