Inhibition of miR-128-3p by Tongxinluo Protects Human Cardiomyocytes from Ischemia/reperfusion Injury via Upregulation of p70s6k1/p-p70s6k1

Background and Aims: Tongxinluo (TXL) is a multifunctional traditional Chinese medicine that has been widely used to treat cardiovascular and cerebrovascular diseases. However, no studies have explored whether TXL can protect human cardiomyocytes (HCMs) from ischemia/reperfusion (I/R) injury. Reperf...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Chen, Gui-hao, Xu, Chuan-sheng, Zhang, Jie, Li, Qing, Cui, He-he, Li, Xiang-dong, Chang, Li-ping, Tang, Rui-jie, Xu, Jun-yan, Tian, Xia-qiu, Huang, Pei-sen, Xu, Jun, Jin, Chen, Yang, Yue-jin
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5670141/
https://ncbi.nlm.nih.gov/pubmed/29163161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00775
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