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Enhanced response of melanoma cells to MEK inhibitors following unbiased IGF-1R down-regulation
Due to its ability to compensate for signals lost following therapeutic MAPK-inhibition, insulin-like growth factor type 1 receptor (IGF-1R) co-targeting is a rational approach for melanoma treatment. However IGF-1R conformational changes associated with its inhibition can preferentially activate MA...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5669887/ https://ncbi.nlm.nih.gov/pubmed/29137261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19286 |
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