Electrostatic interactions between polyglutamic acid and polylysine yields stable polyion complex micelles for deoxypodophyllotoxin delivery

To achieve enhanced physical stability of poly(ethylene glycol)-poly(d,l-lactide) polymeric micelles (PEG-PDLLA PMs), a mixture of methoxy PEG-PDLLA-polyglutamate (mPEG-PDLLA-PLG) and mPEG-PDLLA-poly(l-lysine) (mPEG-PDLLA-PLL) copolymers was applied to self-assembled stable micelles with polyion-sta...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Wang, Yutong, Huang, Liping, Shen, Yan, Tang, Lidan, Sun, Runing, Shi, Di, Webster, Thomas J, Tu, Jiasheng, Sun, Chunmeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2017
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669785/
https://ncbi.nlm.nih.gov/pubmed/29133981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S140573
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