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A Method to Address Between-Subject Heterogeneity for Identification of Principal Surrogate Markers in Repeated Low-Dose Challenge HIV Vaccine Studies

Repeated low-dose challenge designs in non-human primate studies have recently received attention in the literature as a means of evaluating vaccines for HIV prevention and identifying immune surrogates for their protective effects. Existing methods for surrogate identification in this type of study...

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Détails bibliographiques
Publié dans:Stat Med
Auteurs principaux: Spieker, Andrew J., Huang, Ying
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669638/
https://ncbi.nlm.nih.gov/pubmed/28758224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7419
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