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Microglia in prion diseases

Prion diseases are a group of progressive and fatal neurodegenerative disorders characterized by deposition of scrapie prion protein (PrP(Sc)) in the CNS. This deposition is accompanied by neuronal loss, spongiform change, astrogliosis, and conspicuous microglial activation. Here, we argue that micr...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Aguzzi, Adriano, Zhu, Caihong
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669569/
https://ncbi.nlm.nih.gov/pubmed/28714865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90605
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