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Microglia in prion diseases

Prion diseases are a group of progressive and fatal neurodegenerative disorders characterized by deposition of scrapie prion protein (PrP(Sc)) in the CNS. This deposition is accompanied by neuronal loss, spongiform change, astrogliosis, and conspicuous microglial activation. Here, we argue that micr...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Aguzzi, Adriano, Zhu, Caihong
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669569/
https://ncbi.nlm.nih.gov/pubmed/28714865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90605
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