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Microglia in prion diseases

Prion diseases are a group of progressive and fatal neurodegenerative disorders characterized by deposition of scrapie prion protein (PrP(Sc)) in the CNS. This deposition is accompanied by neuronal loss, spongiform change, astrogliosis, and conspicuous microglial activation. Here, we argue that micr...

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Foilsithe in:J Clin Invest
Main Authors: Aguzzi, Adriano, Zhu, Caihong
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669569/
https://ncbi.nlm.nih.gov/pubmed/28714865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90605
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