Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling

In response to injury, epithelial cells migrate and proliferate to cover denuded mucosal surfaces and repair the barrier defect. This process is orchestrated by dynamic crosstalk between immune cells and the epithelium; however, the mechanisms involved remain incompletely understood. Here, we report...

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Vydáno v:J Clin Invest
Hlavní autoři: Quiros, Miguel, Nishio, Hikaru, Neumann, Philipp A., Siuda, Dorothee, Brazil, Jennifer C., Azcutia, Veronica, Hilgarth, Roland, O’Leary, Monique N., Garcia-Hernandez, Vicky, Leoni, Giovanna, Feng, Mingli, Bernal, Gabriela, Williams, Holly, Dedhia, Priya H., Gerner-Smidt, Christian, Spence, Jason, Parkos, Charles A., Denning, Timothy L., Nusrat, Asma
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669557/
https://ncbi.nlm.nih.gov/pubmed/28783045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90229
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