Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling

In response to injury, epithelial cells migrate and proliferate to cover denuded mucosal surfaces and repair the barrier defect. This process is orchestrated by dynamic crosstalk between immune cells and the epithelium; however, the mechanisms involved remain incompletely understood. Here, we report...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Quiros, Miguel, Nishio, Hikaru, Neumann, Philipp A., Siuda, Dorothee, Brazil, Jennifer C., Azcutia, Veronica, Hilgarth, Roland, O’Leary, Monique N., Garcia-Hernandez, Vicky, Leoni, Giovanna, Feng, Mingli, Bernal, Gabriela, Williams, Holly, Dedhia, Priya H., Gerner-Smidt, Christian, Spence, Jason, Parkos, Charles A., Denning, Timothy L., Nusrat, Asma
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669557/
https://ncbi.nlm.nih.gov/pubmed/28783045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90229
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