Tetracyclines downregulate the production of LPS-induced cytokines and chemokines in THP-1 cells via ERK, p38, and nuclear factor-κB signaling pathways

Recent reports have shown that antibiotics such as macrolide, aminoglycoside, and tetracyclines have immunomodulatory effects in addition to essential antibiotic effects. These agents may have important effects on the regulation of cytokine and chemokine production. However, the precise mechanism is...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Sun, Jian, Shigemi, Hiroko, Tanaka, Yukie, Yamauchi, Takahiro, Ueda, Takanori, Iwasaki, Hiromichi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669446/
https://ncbi.nlm.nih.gov/pubmed/29124230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.11.003
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