A novel animal model for neuroinflammation and white matter degeneration

Small interference RNA has been widely used to suppress gene expression. Three different short hairpin RNAs (shRNAs) against dopamine D1 receptor (Drd1), driven by mouse U6 promoter in self-complementary AAV8 vector (scAAV8), were used to silence mouse striatal Drd1 expression. Transduction of mouse...

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Bibliographic Details
Published in:PeerJ
Main Authors: Ji, Baohu, Higa, Kerin, Soontornniyomkij, Virawudh, Miyanohara, Atsushi, Zhou, Xianjin
Format: Artigo
Language:Inglês
Published: PeerJ Inc. 2017
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669272/
https://ncbi.nlm.nih.gov/pubmed/29104820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.3905
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