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Over-expression of XIST, the Master Gene for X Chromosome Inactivation, in Females With Major Affective Disorders

BACKGROUND: Psychiatric disorders are common mental disorders without a pathological biomarker. Classic genetic studies found that an extra X chromosome frequently causes psychiatric symptoms in patients with either Klinefelter syndrome (XXY) or Triple X syndrome (XXX). Over-dosage of some X-linked...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Ji, Baohu, Higa, Kerin K., Kelsoe, John R., Zhou, Xianjin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563114/
https://ncbi.nlm.nih.gov/pubmed/26425698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.06.012
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