A mechanochemical approach to access the proline–proline diketopiperazine framework

Ball milling was exploited to prepare a substituted proline building block by mechanochemical nucleophilic substitution. Subsequently, the mechanocoupling of hindered proline amino acid derivatives was developed to provide proline–proline dipeptides under solvent-free conditions. A deprotection–cycl...

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Foilsithe in:Beilstein J Org Chem
Main Authors: Pétry, Nicolas, Benakki, Hafid, Clot, Eric, Retailleau, Pascal, Guenoun, Farhate, Asserar, Fatima, Sekkat, Chakib, Métro, Thomas-Xavier, Martinez, Jean, Lamaty, Frédéric
Formáid: Artigo
Teanga:Inglês
Foilsithe: Beilstein-Institut 2017
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Full Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669228/
https://ncbi.nlm.nih.gov/pubmed/29114324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.13.217
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