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A mechanochemical approach to access the proline–proline diketopiperazine framework
Ball milling was exploited to prepare a substituted proline building block by mechanochemical nucleophilic substitution. Subsequently, the mechanocoupling of hindered proline amino acid derivatives was developed to provide proline–proline dipeptides under solvent-free conditions. A deprotection–cycl...
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| Publicado no: | Beilstein J Org Chem |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Beilstein-Institut
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5669228/ https://ncbi.nlm.nih.gov/pubmed/29114324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.13.217 |
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