SCN5A Genetic Polymorphisms Associated With Increased Defibrillator Shocks in Brugada Syndrome

BACKGROUND: Brugada syndrome (BrS) is an inherited primary arrhythmia disorder leading to sudden cardiac arrest. SCN5A, encoding the α‐subunit of the cardiac sodium channel (Nav1.5), is the most common pathogenic gene of BrS. An implantable cardioverter defibrillator (ICD) is the standard treatment...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Makarawate, Pattarapong, Chaosuwannakit, Narumol, Vannaprasaht, Suda, Sahasthas, Dujdao, Koo, Seok Hwee, Lee, Edmund Jon Deoon, Tassaneeyakul, Wichittra, Barajas‐Martinez, Hector, Hu, Dan, Sawanyawisuth, Kittisak
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669154/
https://ncbi.nlm.nih.gov/pubmed/28584071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.005009
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