SCN5A Genetic Polymorphisms Associated With Increased Defibrillator Shocks in Brugada Syndrome

BACKGROUND: Brugada syndrome (BrS) is an inherited primary arrhythmia disorder leading to sudden cardiac arrest. SCN5A, encoding the α‐subunit of the cardiac sodium channel (Nav1.5), is the most common pathogenic gene of BrS. An implantable cardioverter defibrillator (ICD) is the standard treatment...

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Dades bibliogràfiques
Publicat a:J Am Heart Assoc
Autors principals: Makarawate, Pattarapong, Chaosuwannakit, Narumol, Vannaprasaht, Suda, Sahasthas, Dujdao, Koo, Seok Hwee, Lee, Edmund Jon Deoon, Tassaneeyakul, Wichittra, Barajas‐Martinez, Hector, Hu, Dan, Sawanyawisuth, Kittisak
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669154/
https://ncbi.nlm.nih.gov/pubmed/28584071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.005009
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