SCN5A Genetic Polymorphisms Associated With Increased Defibrillator Shocks in Brugada Syndrome

BACKGROUND: Brugada syndrome (BrS) is an inherited primary arrhythmia disorder leading to sudden cardiac arrest. SCN5A, encoding the α‐subunit of the cardiac sodium channel (Nav1.5), is the most common pathogenic gene of BrS. An implantable cardioverter defibrillator (ICD) is the standard treatment...

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Detalles Bibliográficos
Publicado en:J Am Heart Assoc
Autores principales: Makarawate, Pattarapong, Chaosuwannakit, Narumol, Vannaprasaht, Suda, Sahasthas, Dujdao, Koo, Seok Hwee, Lee, Edmund Jon Deoon, Tassaneeyakul, Wichittra, Barajas‐Martinez, Hector, Hu, Dan, Sawanyawisuth, Kittisak
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669154/
https://ncbi.nlm.nih.gov/pubmed/28584071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.005009
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