SCN5A Genetic Polymorphisms Associated With Increased Defibrillator Shocks in Brugada Syndrome

BACKGROUND: Brugada syndrome (BrS) is an inherited primary arrhythmia disorder leading to sudden cardiac arrest. SCN5A, encoding the α‐subunit of the cardiac sodium channel (Nav1.5), is the most common pathogenic gene of BrS. An implantable cardioverter defibrillator (ICD) is the standard treatment...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Makarawate, Pattarapong, Chaosuwannakit, Narumol, Vannaprasaht, Suda, Sahasthas, Dujdao, Koo, Seok Hwee, Lee, Edmund Jon Deoon, Tassaneeyakul, Wichittra, Barajas‐Martinez, Hector, Hu, Dan, Sawanyawisuth, Kittisak
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669154/
https://ncbi.nlm.nih.gov/pubmed/28584071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.005009
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