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Molecular Docking Analysis of Phytic Acid and 4-hydroxyisoleucine as Cyclooxygenase-2, Microsomal Prostaglandin E Synthase-2, Tyrosinase, Human Neutrophil Elastase, Matrix Metalloproteinase-2 and -9, Xanthine Oxidase, Squalene Synthase, Nitric Oxide Synthase, Human Aldose Reductase, and Lipoxygenase Inhibitors

BACKGROUND: The phytoconstituents phytic acid and 4-hydroxyisoleucine have been reported to posses various biological properties. OBJECTIVE: This prompted us to carry out the docking study on these two ligands (phytic acid & 4-hydroxyisoleucine) against eleven targeted enzymes. MATERIALS AND MET...

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Detalhes bibliográficos
Publicado no:Pharmacogn Mag
Main Authors: Narayanaswamy, Radhakrishnan, Wai, Lam Kok, Esa, Norhaizan Mohd
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669090/
https://ncbi.nlm.nih.gov/pubmed/29142407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/pm.pm_195_16
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