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Putative genomic characteristics of BRAF V600K versus V600E cutaneous melanoma
Approximately, 50% of all cutaneous melanomas harbor activating BRAF V600 mutations, among these 10–30% carry the V600K mutation. Clinically, patients with V600K tumors experience distant metastases sooner and have an increased risk of relapse and shorter survival than patients with V600E tumors. De...
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| Pubblicato in: | Melanoma Res |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5669042/ https://ncbi.nlm.nih.gov/pubmed/28858076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0000000000000388 |
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