Inhibition of DAMP signaling as an effective adjunctive treatment strategy in pneumococcal meningitis

BACKGROUND: Pneumococcal meningitis remains a potentially lethal and debilitating disease, mainly due to brain damage from sustained inflammation. The release of danger-associated molecular patterns (DAMPs), like myeloid-related protein 14 (MRP14) and high mobility group box 1 protein (HMGB1), plays...

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Dettagli Bibliografici
Pubblicato in:J Neuroinflammation
Autori principali: Masouris, Ilias, Klein, Matthias, Dyckhoff, Susanne, Angele, Barbara, Pfister, H. W., Koedel, Uwe
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669003/
https://ncbi.nlm.nih.gov/pubmed/29096648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0989-0
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