Reduced spiral ganglion neuronal loss by adjunctive neurotrophin-3 in experimental pneumococcal meningitis

BACKGROUND: Hearing loss is a frequent long-term complication of pneumococcal meningitis (PM). Its main pathological correlate is damage to the organ of Corti and loss of spiral ganglion neurons. The only current treatment option is cochlear implants which require surviving neurons. Here, we investi...

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Bibliografiske detaljer
Main Authors:	Demel, Cornelia, Hoegen, Tobias, Giese, Armin, Angele, Barbara, Pfister, Hans-Walter, Koedel, Uwe, Klein, Matthias
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2011
Fag:	Research
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3038911/ https://ncbi.nlm.nih.gov/pubmed/21261959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-7
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Reduced spiral ganglion neuronal loss by adjunctive neurotrophin-3 in experimental pneumococcal meningitis

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