Reduced spiral ganglion neuronal loss by adjunctive neurotrophin-3 in experimental pneumococcal meningitis

BACKGROUND: Hearing loss is a frequent long-term complication of pneumococcal meningitis (PM). Its main pathological correlate is damage to the organ of Corti and loss of spiral ganglion neurons. The only current treatment option is cochlear implants which require surviving neurons. Here, we investi...

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Detalhes bibliográficos
Main Authors: Demel, Cornelia, Hoegen, Tobias, Giese, Armin, Angele, Barbara, Pfister, Hans-Walter, Koedel, Uwe, Klein, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038911/
https://ncbi.nlm.nih.gov/pubmed/21261959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-7
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