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Application of termite hindgut metagenome derived carboxyl ester hydrolases in the modification of cephalosporin substrates
In the pharmaceutical industry, de-acetylated cephalosporins are highly valuable starting materials for producing semi-synthetic β-lactam antibiotics. In this study a fosmid metagenome library from termite hindgut symbionts was screened for carboxyl ester hydrolases capable of de-acetylating cephalo...
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| Publicado en: | Biochem Biophys Rep |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Elsevier
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5668906/ https://ncbi.nlm.nih.gov/pubmed/29124186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.08.016 |
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